NextSeq 1000 to NextSeq 2000 Sequencing System Upgrade

Key Details

The National Eye Institute (NEI) needs a sole-source upgrade of its Illumina NextSeq 1000 Sequencing System to NextSeq 2000 capability. The upgrade will provide expanded sequencing flexibility and capacity by enabling the use of additional flow cell configurations and higher-throughput sequencing applications.

• What exactly do they need?
• The contractor shall provide all labor, materials, parts, equipment, software, travel, installation, testing, and technical services necessary to complete the upgrade and deliver a fully functional NextSeq 2000 instrument configuration.
• Compatibility with existing Illumina sequencing kits, reagents, hardware architecture, software, and validated research workflows is essential to support ongoing scientific studies and maintain operational continuity.
• What's the contract structure and timeline?
• This is a sole-source acquisition, meaning only one vendor is eligible.
• The notice doesn't say how long the contract will last.
• How will they pick the winner?
• The notice doesn't say how the winner will be chosen.
• When and how do you bid?
• Responses must be submitted in writing and contain sufficient technical documentation to demonstrate the capability to provide the required upgrade and associated services.
• Responses to this notice shall be submitted via email to the Contract Specialist Mesfin Alemayehu, at mesfin.alemayehu@hhs.gov no later than 2 p.m. EST Friday, June 26, 2026.